Wednesday, 1 July 2009

BG on Insulin: Amy insight?

Thanks for the info. I am pretty close to a good balance now, but some additional tweaking is certainly in order. I am pretty happy with shooting insulin, but there are some logistics involved when traveling or even going to town to eat out (I live on a farm in the boondocks). The worst experience I have had was that I was briefly pulled off Levimir alone and switched to Humolog 75-25 monotherapy (before the Lantus / Humolog). That 75-25 stuff is dangerous and I wound up with a hypo episode that damn near killed me! It should not have happened and it remains a mystery why. I have a friend who is an insulin dependent Type 1.5 who had a similar thing happen with the 75-25 (now on Lantus / Humolog) that put him in the emergency room in a coma.

>Can you please give me some insight into what to expect from insulin on BG compliance after meals? This assumes a Lantus/Humolog sliding scale regimen.I am curious how high BG should be expected to spike post prandial (say at one and two hours).How long should it take for BG to return to 120 or less after a meal assuming Lantus is doing its job and maintaining 120 or less for a fasting BG.?<

Oh, gee. This is definitely a YMMV thing, Syd. It'd be nice to go back to 120 by hour 3 or so, for sure. Some will want to be back there by hour 2. A lot depends on what you and your doctor have decided are your pre- and post-meal glucose goals. Let's just put it this way-- whatever your pre-meal glucose was, it's ideal to never see more than a 40 point (some would say 20 point) rise at any time before the next meal and insulin dose. I personally can do the 40 point thing, but not 20, not with my current way of eating. Definitely YMMV-- sooooo much depends on exercise, dietary choices, insulin dosages and timing, etc.

>I understand Humolog is supposed to be all gone after three hours, but I am seeing some screwy effects that make me wonder about that. Amy insight?<

Remember when you read about Humalog's time of efficacy (when it peaks until when it goes away), those are *averages*. Some folks are hit hard in 10 minutes or less, and it might be 6 hours before it's all metabolized and gone. Others might need close to an hour to really have it do its thing, and it might be gone in 2.5. Again, YMMV. Test, test, test. That's the only way you'll know the answers for YOU. And give it lots of time, easily 2 or 3 months, before you expect to be anywhere near a good balance for you.

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