Whose he is starting Lantus?

>His numbers went from being in the low 200 high 100's to being in the high 200's to mid 300's. Totally freaked me out. I spoke with the Nurse today and she said we would up to 20 units tonight and to go with that until Monday. Monday I need to send more numbers in. She said after a week we should see an improvement. I reminded her that it's a week today. She told us to keep going and not to get concerned.<

Well, you checked with your medical providers, so IMO you're doing all the right things. Yeah, 391 is pretty high. Too high to exercise much, so short of eating way low carb, all you can do is just keep on with the insulin and the testing, and just do what the doc's office told you to do.

>She did say she expected him to get to between 20-35 units before it leveld off. I wonder why she didn't raise him to 20 sooner than wait. Does it need to be increased slowly?<

Yes, with a new insulin user, they have to start with a small dose and then systematically raise it. This slow steady way of doing things takes a lot of patience when you're anxious to see better numbers and to feel better, but it really is the correct way to do it. Not sure why she said 20-35 units will do it. A lot depends on his weight, activity level, how much insulin resistance he has, what he eats. Lots of us take way more than 35 units of Lantus every day.

>Is it more important to be the same time or at bed time every night? We have been giving it to him between 7:30 and 8:00pm because he does sometimes go to sleep that early and other times it's 11:00 pm.<

Make it as close to every 24 hours as you can without being a slave to the clock. With Lantus, you have an hour or so leeway to play with if you have to. But if there's no reason to make the time different, go ahead and nail the 24 hour mark as close as you can. Have him take it at supper if his bedtimes are irregular. As long as whatever he does is roughly the same every day, that'd be fine. This is going to be a long trek, Donna, to get your DH where he needs to be. Try not to worry too much. Come by to share anytime, of course. We want to be here for you.